A corrupted customs officer, Choi Ik-hyeon, faces losing his job. Then, his life turns around as he meets ganster Choi Hyeong-bae who has connection with the Yakuza. They quickly form a partnetship; Hyeong-bae helps Ik-hyeon set up a business with the money from drug trafficking while Ik-hyeon lobbies for his partner Hyeong-bae. As the government declares war on crime, however, their partnership begins to crack.
Set in the 19th century. Jo Yoon (Gang Dong-Won) is the illegitimate son of a wealthy nobleman and a gisaeng. Because his father and his wife failed to have a son themselves, they bring Jo Yoon into their home at the age of 10. Later, his stepmother gives birth to their first legitimate son. Jo Yoon struggles for recognition from his father.
A chance though arises for Jo Yoon to become a legitimate son. His younger stepbrother is killed by a group of thieves. Jo Yoon possesses elite sword skills and decides to plunder from the poor to amass a vast fortune. To become the only heir, Jo Yoon then decides to kill the pregnant wife of his late stepbrother.
Meanwhile, Dol Moo-Chi (Ha Jung-Woo) works as a lowly butcher. He lives with his mother and younger sister. Dol Moo-Chi is then brought in front of Jo Yoon and is hired to kill Jo Yoon’s pregnant sister-in-law. Dol Moo-Chi though is unable to carry out the execution. His failure causes tragedy to unfold upon his family and himself. As Dol Moo-Chi is about to be executed, a group of righteous thieves known as Kundo arrives.
Doomsday Book is an anthology movie, split into 3 different chapters. The first Chapter, entitled Heaven’s Creation, is about a robot who comes alive and follows what happens afterward. The second Chapter, entitled The New Generation, is a story from the point of view of a boy who is now a zombie. The third Chapter, entitled Happy Birthday, re-interprets “The Christmas Gift” by O Henry.
Infected through the respiratory system, there is a new kind of disease that kills in 36 hours once infected. The people of the city struggle to survive this. The worst epidemic ever seen is sweeping through Bundang, the suburb of Seoul. After smuggling illegal immigrants into the country, Byung-woo dies from an unknown virus. Soon after that, the same symptoms are plaguing scores of residents in Bundang.