The film is composed of multiple comedy shorts presented through an overarching segment titled “The Pitch”, in which Charlie Wessler, a mad screenwriter, is attempting to pitch a script to film executive Griffin Schraeder. After revealing several of the stories in his script, Wessler becomes agitated when Schraeder dismisses his outrageous ideas, and he pulls a gun on him and forces him to listen to multiple other stories before making Schraeder consult his manager, Bob Mone, to purchase the film.
Follows a pair of married couples, Alfie (Hopkins) and Helena (Jones), and their daughter Sally (Watts) and husband Roy (Brolin), as their passions, ambitions, and anxieties lead them into trouble and out of their minds. After Alfie leaves Helena to pursue his lost youth and a free-spirited call girl named Charmaine (Punch), Helena abandons rationality and surrenders her life to the loopy advice of a charlatan fortune teller. Unhappy in her marriage, Sally develops a crush on her handsome art gallery owner boss, Greg (Banderas), while Roy, a novelist nervously awaiting the response to his latest manuscript, becomes moonstruck over Dia (Pinto), a mystery woman who catches his gaze through a nearby window.
In 1933 New York, an overly ambitious movie producer coerces his cast and hired ship crew to travel to mysterious Skull Island, where they encounter Kong, a giant ape who is immediately smitten with leading lady Ann Darrow.
The last two years of Princess Diana’s life: her campaign against land mines and her relationship with surgeon Dr Hasnat Khan.