Michael Sheen and Lizzy Caplan are the stars of "Masters of Sex" -- they'll play William Masters and Virginia Johnson, the real-life pioneers of the science of human sexuality. Their research, per Showtime's description, "touched off the sexual revolution and took them from a mid-western teaching hospital in St. Louis to the cover of Time magazine and nearly a dozen appearances on Johnny Carson's couch."
Sheen will be making his first regular TV appearance in his role here -- Caitlin Fitzgerald ("It's Complicated"), will play his wife (who he, incidentally, eventually divorces in order to marry Johnson), and Nicholas D'Agosto ("Rocket Science") and Teddy Sears ("American Horror Story" are also in the cast.
Michelle Ashford, who was a writer and co-producer on "The Pacific," created "Masters of Sex," which is adapted from a book -- Thomas Maier's "Masters of Sex: The Life and Times of William Masters and Virginia Johnson, The Couple Who Taught America How To Love." "The Best Exotic Marigold Hotel" director John Madden helmed the pilot, which will presumably be "Kinsey"-esque.
Like Sheen, this series will mark Schreiber's first regular television role, though he did play a four-episode arc on "C.S.I." back in 2007. Other cast members include Jon Voight as the Donovan family patriarch and an ex-con, Elliot Gould as Ray's client and mentor, Eddie Marsan ("Tyrannosaur") and Dash Mihok ("I Am Legend") as Ray's brothers, and Paula Malcomson ("The Hunger Games") as Ray's wife.
Kate Moennig ("The L Word"), Steven Bauer ("Breaking Bad"), Pooch Hall ("The Game") and Johnathon Schaech ("That Thing You Do!") will also make appearances. "Ray Donovan" is from "Southland" creator Ann Biderman -- Allen Coulter (of "Hollywoodland") directed the pilot.