Boss 1

At its season two midpoint, Starz's "Boss" has Chicago mayor Tom Kane (Kelsey Grammer) struggling with some out-of-control symptons from the degenerative neurological disorder slowing that's eating away at his ability to function, and looking for new treatments to control the condition while dealing with a city on the verge of violence thanks to his recent actions.

In this exclusive clip from episode six of the season, "Backflash," airing this Friday, September 21st at 9pm, Tom's wife Meredith (Connie Nielsen) tries to keep a meeting of city council members calm in her husband's absence, though the antagonistic Alderman Ross (James Vincent Meredith) is not inclined to offer him any slack.