According to the Hollywood Reporter, the comedy (no title announced yet) will be executive produced and directed by "Easy A" and "Friends with Benefits" helmer Will Gluck, with Sam Laybourne ('Arrested Development," "Cougar Town") on board as a writer.
Fox, who first achieved stardom playing Alex P. Keaton in "Family Ties," was diagnosed with Parkinson's disease in 1991 and semi-retired from acting in 2000, though he's since done guest spots on "Rescue Me," "Boston Legal" and "The Good Wife." This new show will mark his return to full-time television since exiting "Spin City." Per the Hollywood Reporter, the show is being set for a premiere in fall of next year:
It features Fox as a husband and father of three from New York City dealing with family, career, and challenges – including Parkinson’s Disease – loosely drawn from Fox’s real life. Further casting will be announced at a later date.
Here's Fox bickering with Larry David on "Curb Your Enthusiasm" last year: